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Pharmacological Index

Gastrointestinal tract

"The human gastrointestinal tract is the stomach and intestine, sometimes including all the structures from the mouth to the anus. (The ""digestive system"" is a broader term that includes other structures, including the accessory organs of digestion).
In an adult male human, the gastrointestinal (GI) tract is 5 metres (20 ft) long in a live subject, or up to 9 metres (30 ft) without the effect of muscle tone, and consists of the upper and lower GI tracts. The tract may also be divided into foregut, midgut, and hindgut, reflecting the embryological origin of each segment of the tract.
The GI tract always releases hormones to help regulate the digestion process. These hormones, including gastrin, secretin, cholecystokinin, and grehlin, are mediated through either intracrine or autocrine mechanisms, indicating that the cells releasing these hormones are conserved structures throughout evolution."

Colon & Rectum

"Your colon, also known as the large intestine, is part of your digestive system. It's a long, hollow tube at the end of your digestive tract where your body makes and stores stool. Many disorders affect the colon's ability to work properly. Some of these include
1. Colorectal cancer.
2. Colonic polyps - extra tissue growing in the colon that can become cancerous.
3. Ulcerative colitis - ulcers of the colon and rectum.
4. Diverticulitis - inflammation or infection of pouches in the colon.
5. Irritable bowel syndrome - an uncomfortable condition causing abdominal cramping and other symptoms.
Treatment for colonic diseases varies greatly depending on the disease and its severity. Treatment may involve diet, medicines and in some cases, surgery. The rectum refers to the last four or five inches of the digestive tract. The rectal outlet or opening is called the anal canal or anus. Problems in this area are common, but many adults are too shy or embarrassed to ask their doctor about them. Fortunately, most of these problems are treatable when recognized early and properly diagnosed. Remember that symptoms of rectal pain or bleeding should always be thoroughly evaluated by your doctor. Hemorrhoids are veins in the anal canal that can become swollen or stretched. Just like varicose veins in the lower legs, hemorrhoids often cause no problems."

API For Colon & Rectum

    Cinchocaine HCL
    Indometacin (Indomethacin)
    Mesalazine (Mesalamine)

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