Indication
Breast cancer, Metastatic, Metastatic colorectal cancer.
Contra Indication
History of severe and unexpected reaction to fluoropyrimidine therapy, severe renal impairment. Hypersensitivity. Contraindicated during pregnancy and lactation.
Caution
Renal and hepatic function should be monitored, Stop therapy it bone marrow suppression, diarrhoea, myocardial ischaemia occurs.
Side Effect
Diarrhoea, nausea and vomiting, stomatitis, palmar-plantar syndrome, dermatitis. Fatigue, mucosal inflammation, pyrexia, asthenia and lethargy, headache, dizziness and insomnia, lower limb oedema, anorexia, dehydration.