Indication
Respiratory tract infections, Gastroenteritis, Susceptible infections, Uncomplicated urinary tract infections, Pneumocystis (carinii) jiroveci pneumonia.
Contra Indication
Hypersensitivity, serious haematological disorders, severe renal impairment, megaloblastic anaemia secondary to folate depletion.
Caution
Renal and hepatic impairment, porphyria, patients with potential folate deficiency, elderly, pregnancy, lactation, children with fragile X chromosome associated with mental retardation. Perform regular haematological examination.
Side Effect
Nausea, vomiting, glossitis, pruritus, skin rash, fever, hyponatremia, hyperkalaemia, photosensitivity, liver enzyme elevation, , raised serum creatinine and BUN, blood dyscrasias, cholestatic jaundice, anaphylaxis, aseptic meningitis. Stevens-Johnson syndrome, toxic epidermal necrolysis.
Sandoz Pvt. Ltd. (Novartis India)
Cipla Ltd.