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Pharmacological Index

Antibiotics & Antiinfectives

A drug used to treat infections caused by bacteria and other microorganisms is known as Antibiotics. It is a compound or substance that kills or slow down the growth of bacteria. Originally, an antibiotic was a substance produced by one microorganism that selectively inhibits the growth of another.Few Antibiotics are tetracycline,penicillin and many more.
When infection attacks the body, anti-infective drugs can suppress the infection. Four types of anti-infective or drugs exist: antibacterial (antibiotic), antiviral, antitubercular, and antifungal. Depending on the severity and the type of infection, the antibiotic may be given by mouth, injection or may be applied topicallyThe symptoms of an infection affect the whole body generally, such as fatigue, loss of appetite, weight loss, fevers, night sweats, chills, aches and pains. Others are specific to individual body parts, such as skin rashes, coughing, or a runny nose..

Amino Glycosides

An aminoglycoside is a molecule or a portion of a molecule composed of amino-modified sugars. Several aminoglycosides function as antibiotics that are effective against certain types of bacteria. Aminoglycosides have several potential antibiotic mechanisms, some as protein synthesis inhibitors, although their exact mechanism of action is not fully known:
1. They interfere with the proofreading process, causing increased rate of error in synthesis with premature termination.
2. Also, there is evidence of inhibition of ribosomal translocation where the peptidyl-tRNA moves from the A-site to the P-site.
3. They can also disrupt the integrity of bacterial cell membrane."

API For Amino Glycosides

    Amikacin
    Gentamicin
    Kanamycin
    Neomycin
    Netilmicin
    Sisomicin
    Tobramycin Sulphate

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