Indication
Hypertension, CHF, oedema due to CHF.mild to moderate renal and hepatic impairment
Contra Indication
Hypersensitivity. Pre existing hyperkalaemia. Severe renal or hepatic impairment. Respiratory or metabolic acidosis. Lactation
Caution
Renal and hepatic impairment, cirrhosis, DM, hyponatraemia, hyperuricaemia, history of nephrolithiasis, depleted folic acid stores. Monitor electrolyte concentrations closely, especially potassium levels. Observe for signs of liver damage, blood dyscrasias or other idiosyncratic reactions. Discontinue treatment if urinary calculus is passed. Pregnancy and elderly.
Side Effect
Anaphylaxis, rash and photosensitivity. Decrease/increase in potassium level in blood. Elevated Blood Urea Nitrogen, kidney stones and kidney failure. Jaundice, liver enzyme abnormalities, nausea, vomiting and diarrhea. Decreased platelet counts and anemia. Weakness, fatigue, dizziness, headache and dry mouth.