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Nitrofurantoin uses and side effect

Indication

Muscle relaxation (long duration) for surgery and intubation, Prophylaxis of UTI, Uncomplicated UTIs, Urinary tract infection.

Contra Indication

Hypersensitivity. Impaired renal function. Pregnancy and neonates. Severe oliguria or anuria. G6PD deficiency.

Caution

Elderly. Monitor hepatic and pulmonary function during prolonged therapy. Pre-existing pulmonary, hepatic, neurological, or allergic disorders, predisposition to peripheral neuropathy e.g. renal impairment, anaemia, DM, electrolyte imbalance, debility, vitamin B deficiency. Withdraw if signs of peripheral neuropathy occur. Lactation.

Side Effect

Nausea, vomiting, anorexia, abdominal pain, diarrhoea, headache, vertigo, rash, urticaria, lupus-like syndrome, haemolytic anaemia. Peripheral polyneuropathy, hepatotoxicity, anaphylaxis. interstitial pneumonitis.
Medicines containing Nitrofurantoin

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