Muscle relaxation (long duration) for surgery and intubation, Prophylaxis of UTI, Uncomplicated UTIs, Urinary tract infection.
Hypersensitivity. Impaired renal function. Pregnancy and neonates. Severe oliguria or anuria. G6PD deficiency.
Elderly. Monitor hepatic and pulmonary function during prolonged therapy. Pre-existing pulmonary, hepatic, neurological, or allergic disorders, predisposition to peripheral neuropathy e.g. renal impairment, anaemia, DM, electrolyte imbalance, debility, vitamin B deficiency. Withdraw if signs of peripheral neuropathy occur. Lactation.
Nausea, vomiting, anorexia, abdominal pain, diarrhoea, headache, vertigo, rash, urticaria, lupus-like syndrome, haemolytic anaemia. Peripheral polyneuropathy, hepatotoxicity, anaphylaxis. interstitial pneumonitis.