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Lungs

lung The respiratory organ of air-breathing vertebrates. A pair of lungs is situated in the thorax, within the ribcage. Each consists essentially of a thin moist membrane that is folded to increase its surface area. Exchange of oxygen and carbon dioxide takes place between blood capillaries on one side of the membrane and air on the other. The lung is supplied with air through a bronchus. The lungs are covered by a thin tissue layer called the pleura. The same kind of thin tissue lines the inside of the chest cavity -- also called pleura. A thin layer of fluid acts as a lubricant allowing the lungs to slip smoothly as they expand and contract with each breath.

Cystic fibrosis

Cystic fibrosis (also known as CF or mucoviscidosis) is an autosomal recessive genetic disorder that affects most critically the lungs, and also the pancreas, liver, and intestine. It is characterized by abnormal transport of chloride and sodium across an epithelium, leading to thick, viscous secretions.
The name cystic fibrosis refers to the characteristic scarring (fibrosis) and cyst formation within the pancreas, first recognized in the 1930s. Difficulty breathing is the most serious symptom and results from frequent lung infections that are treated with antibiotics and other medications. Other symptoms, including sinus infections, poor growth, and infertility affect other parts of the body.

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