Indication
Obsessive compulsive disorder, Major depression, Panic disorder with or without agoraphobia, Narcolepsy, Premature ejaculation, Depersonalization disorder, Chronic pain, Enuresis, Cataplexy, Trichotillomania.
Contra Indication
Epilepsy, cardiovascular disease, narrow angle glaucoma, MAOIs, urinary retention, ischaemic heart disease.
Caution
Cardiovascular insufficiency, narrow-angle glaucoma, urinary retention, history of epilepsy, renal or hepatic dysfunction, electroconvulsive therapy, hypotension, hyperthyroidism or concomitant treatment with thyroid preparations, suicidal tendencies, surgery, pregnancy and lactation, tasks requiring mental alertness, elderly, avoid abrupt withdrawal.
Side Effect
Often, fatigue, dizziness, lightheadedness, headaches, confusion, agitation, insomnia, nightmares, increased anxiety, seizures, rarely hypomania or induction of schizophrenia, and extrapyramidal side effects (pseudoparkinsonism, dyskinesia, rarely tardive dyskinesia), dry mouth, constipation, rarely ileus, difficulties in urinating, sweating, precipitation of glaucoma (permanent eye-damage or even blindness). The incidence of dental caries may be increased due to dry mouth.