Indication
Syntheticprogestogen used to prevent threatened miscarriage, recurrent pregnancy loss andpremature labor.[1][2] In men, it has also been studied as a treatment for benign prostatic hyperplasia, with encouraging results.
Contra Indication
Hypersensitivity; thrombophleobitis; undiagnosed vag bleeding, incomplete abortion, hormone-dependent carcinoma, cerebral apoplexy, as a diagnostic test for pregnancy; severe hepatic impairment; pregnancy
Caution
Diabetes. Exclude pregnancy. Suspicion of thromboembolic disorders.
Side Effect
GI disturbances, appetite/weight change; fluid retention, oedema; acnes, skin rash, urticaria; depression, headache, fever, fatigue; breast changes, hirsutism, changes in libido, altered menstrual cycles or irregular menstrual bleeding.